Contraction of the membrane causes corrugations in the fovea that distort the patient’s vision, with straight lines appearing bent or bowed. It can also cause blurred vision, although often the visual acuity is less affected than expected based on symptoms. It can occur in isolation or in association with other eye disease such as diabetes, peripheral retinal breaks, posterior uveitis, and trauma.
Treatment involves surgical removal with vitrectomy and membrane peel. This usually improves the distortion, but vision is seldom completely normal and the full benefit of surgery can take several months to manifest. The effect on visual acuity may be less marked.
Occasionally the membranes recur, and very rarely repeat surgery is indicated.